核受体（nuclear receptor，NR）是在生物体内广泛分布的配体依赖性转录因子超家族。核受体与其配体及调节因子相互作用，调控基因的表达。在机体生长发育，细胞分化及体内许多胜利代谢过程中发挥不同的作用。合研生物拥有多种核受体靶点细胞，为客户提供基于细胞的核受体及其配体药物筛选服务。
合研生物拥有丰富的核受体筛选经验，加速您的药物研发进程。
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靶点 |
方法 |
|
Estrogen Receptor alpha (ERα) |
Cell based |
|
Estrogen Receptor beta (ERβ) |
Cell based |
|
Glucocorticoid receptor (GR) |
Cell based |
|
Liver X receptor alpha (LXRα) |
Cell based |
|
Liver X receptor beta (LXRβ) |
Cell based |
|
Androgen Receptor (AR) |
Cell based |
|
Farnesoid X receptor (FXR) |
Cell based |
|
Peroxisome proliferator-activated receptor alpha (PPARα) |
Cell based |
|
Peroxisome proliferator-activated receptor delta (PPARδ) |
Cell based |
|
Peroxisome proliferator-activated receptor gamma (PPARγ) |
Cell based |
|
Progesterone Receptor (PR) |
Cell based |
|
Pregnane and Xenobiotic Receptor (PXR) |
Cell based |
|
Retinoic acid receptor beta (RARβ) |
Cell based |
|
Retinoic acid receptor alpha (RARα) |
Cell based |
|
Mineralocorticoid receptor (MR) |
Cell based |
|
Retinoid X Receptor alpha (RXRα) |
Cell based |
|
Retinoid X Receptor beta (RXRβ) |
Cell based |
|
Retinoid X Receptor gamma (RXRγ) |
Cell based |
|
Thyroid receptor alpha (TRα) |
Cell based |
|
Thyroid receptor beta (TRβ) |
Cell based |
|
Vitamin D Receptor (VDR) |
Cell based |